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单词 vitiligo
释义

vitiligo

enUK

vit·i·li·go

V0128400 (vĭt′l-ī′gō, -ē′gō)n. Partial or total loss of skin pigmentation, often occurring in patches.
[Latin vitilīgō, tetter.]

vitiligo

(ˌvɪtɪˈlaɪɡəʊ) n (Pathology) another name for leucoderma[C17: from Latin: a skin disease, probably from vitium a blemish]

vit•i•li•go

(ˌvɪt lˈaɪ goʊ, -ˈi goʊ)

n. a skin disorder, of unknown cause, characterized by patches of unpigmented skin. [1650–60; < Latin vitilīgō skin eruption, appar. akin to vitium fault, defect]

vitiligo

Uneven coloring of the skin caused by loss of melanocytes and an uneven production of melanin (pigment). This results in lighter patches of skin surrounded by areas of the normal skin color. It is thought to be caused by a disorder of the immune system.
Thesaurus
Noun1.vitiligo - an acquired skin disease characterized by patches of unpigmented skin (often surrounded by a heavily pigmented border)disease of the skin, skin disease, skin disorder - a disease affecting the skinhypopigmentation - unusual lack of skin color
Translations
vitiligovitíligo

vitiligo

enUK

vitiligo,

condition that causes irregular patches of skin to lose pigment and turn white. The exact cause is unknown, but it occurs when the immune system attacks and destroys melanocytes, the cells that make pigment; the skin does not become raised or painful. Commonly affected areas are the face, elbows and knees, hands and feet, and genitals. Vitiligo can appear at any age and may worsen over time; it is more noticeable in individuals with darker skin. Treatments include ultraviolet light therapy, topical corticosteroid or immunosuppressive creams or gels, skin grafts from normally pigmented areas, opaque foundation makeup and skin dyes to camouflage the affected area, and the depigmenting of the remaining normal skin in extensive cases. Although affected areas sunburn easily and may be associated with certain skin cancers, research has found that a common gene mutation may increase both the chance of vitiligo and lower the risk of melanoma, the most serious form of skin cancer.

Vitiligo

 

a pigmentation disorder manifested by the disappearance of normal pigment from patches of skin. The cause is unknown. It usually starts in youth (more often in females) with the appearance of white spots of different sizes and shapes on unchanged skin. The spots gradually enlarge and coalesce, forming extensive milky-white patches. The hairs on the affected areas turn gray. Foci of vitiligo may occur anywhere on the skin. The affected individuals experience no internal sensations. Treatment consists in using drugs that increase the sensitivity of skin to ultraviolet rays and then exposing the skin to these rays.

vitiligo

[‚vid·əl‚ī·gō] (medicine) A skin disease characterized by an acquired ochromia in areas of various sizes and shapes.

vitiligo

enUK

Vitiligo

 

Definition

Vitiligo is a condition in which a loss of cells that give color to the skin (melanocytes) results in smooth, white patches in the midst of normally pigmented skin.

Description

Vitiligo is a common, often inherited disorder characterized by areas of well-defined, milky white skin. People with vitiligo may have eye abnormalities and also have a higher incidence of thyroid disease, diabetes mellitus, and pernicious anemia. Vitiligo affects about 1-2% of the world's population. It is more easily observed in sun-exposed areas of the body and in darker skin types, but it affects any area of the body and all races. Vitiligo seems to affect men and women equally, although women more frequently seek treatment for the disorder.Vitiligo may appear as one or two well-defined white patches or it may appear over large portions of the body. Typical sites for generalized vitiligo are areas surrounding body openings, bony areas, fingers, and toes. It can begin at any age but about 50% of the time it starts before the age of 20.

Causes and symptoms

Vitiligo is a disorder with complex causes. People with vitiligo seem to inherit a genetic predisposition for the disorder, and the appearance of disorder can be brought on by a variety of precipitating causes. Many people report that their vitiligo first appeared following a traumatic or stressful event, such as an accident, job loss, death of a family member, severe sunburn, or serious illness. There are at least three theories about the underlying mechanism of vitiligo. One theory says nerve endings in the skin release a chemical that is toxic to the melanocytes. A second theory states that the melanocytes simply self-destruct. The third explanation is that vitiligo is a type of autoimmune disease in which the immune system targets the body's own cells and tissues.The primary symptom of vitiligo is the loss of skin color. Hair growing from the affected skin areas also lacks color. In addition, people with vitiligo may have pigment abnormalities of the retina or iris of the eyes. A minority of patients also may have inflammation of the retina or iris, but vision is not usually impaired.

Diagnosis

The diagnosis of vitiligo is usually made by observation. Progressive, white areas found at typical sites point to a diagnosis of vitiligo. If the diagnosis is not certain, the doctor will test for other conditions which can mimic vitiligo, such as chemical leukoderma or systemic lupus erythematosus. If the tests rule out other conditions, vitiligo is confirmed.

Key terms

Autoimmune disease — A condition in which something triggers the immune system to react against and attack the body's own tissues.Autologous transplantation — A procedure wherein the person donates blood or tissue to themselves.Iris — The colored part of the eye.Pernicious anemia — A disease in which red blood cells are abnormally formed due to the body's inability to absorb vitamin B12.Retina — The innermost layer of the eye, it contains the rods and cones, specialized light-sensitive cells.

Treatment

Vitiligo cannot be cured, but it can be managed. Cosmetics can be used to improve the appearance of the white areas not covered by clothing. Sunscreens prevent burning of the affected areas and also prevent the normal skin around the patches from becoming darker. Skin creams and oral medications are available for severe cases, but they have side effects that may make them undesirable. Autologous transplantation of skin is an option for those who are severely affected. Bleaching or depigmentation of the normal skin is another option.In addition to treating the skin, attention should be paid to the psychological well-being of the individual. Extreme cases of vitiligo can be unattractive and may affect a person's outlook and social interactions.

Prognosis

The condition is usually gradually progressive. Sometimes the patches grow rapidly over a short period, and then the condition remains stable for many years.

Prevention

No measures are currently known to prevent vitiligo.

Resources

Organizations

Frontier's International Vitiligo Foundation. 4 Rozina Court, Owings Mills, MD 21117. (301) 594-0958.National Foundation for Vitiligo and Pigment Disorders. 9032 South Normandy Drive, Centerville, OH 45459. (513) 885-5739.National Vitiligo Foundation. P.O. Box 6337, Tyler, TX 75703. (903) 531-9767. 〈73071.33@compuserve.com〉.

vitiligo

 [vit″ĭ-li´go] a condition in which destruction of melanocytes in small or large circumscribed areas results in patches of depigmentation often having a hyperpigmented border, and often enlarging slowly. adj., adj vitilig´inous.

vit·i·li·go

, pl.

vit·i·lig·i·nes

(vit'i-lī'gō, vit'i-lij'i-nēz), [MIM*193200] The appearance on otherwise normal skin of nonpigmented white patches of varied sizes, often symmetrically distributed and usually bordered by hyperpigmented areas; hair in the affected areas is usually white. Epidermal melanocytes are completely lost in depigmented areas by an autoimmune process. Synonym(s): acquired leukoderma [L. a skin eruption, fr. vitium, blemish, vice]

vitiligo

(vĭt′l-ī′gō, -ē′gō)n. Partial or total loss of skin pigmentation, often occurring in patches.

vitiligo

Dermatology An acquired condition characterized by patchy depigmentation in the face, elbows, knees, hands, feet, and genitalia, often at sites of trauma and pressure, which may appear at any age; there is an ↑ incidence in some families; autoimmunity may be a factor, as there is selective loss of melanocytes in the involved area. See Melanocyte.

vit·i·li·go

, pl. vitiligines (vit'i-lī'gō, -lij'inēz) The appearance on otherwise normal skin of nonpigmented white patches of varied sizes; hair in the affected areas is usually white. Epidermal melanocytes are completely lost in depigmented areas by an autoimmune process.[L. a skin eruption, fr. vitium, blemish, vice]

vitiligo

(vit-il-i'go) [L.] VITILIGOA skin disorder characterized by the localized loss of melanocytes, with patchy loss of skin pigment. The depigmented areas, which appear most commonly on the hands, face, and genital region, are flat and pale and surrounded by normal pigmentation. Vitiligo affects all ages and races but is most noticeable in people with dark skin. The cause is unknown, but may be an autoimmune process since autoantibodies to melanocytes have been identified and vitiligo often occurs with autoimmune diseases. Synonym: leukoderma; skin, piebald See: illustration

Treatment

Oral and topical synthetic trioxsalen and a natural psoralen, methoxsalen, are used with exposure to long-wave ultraviolet light, but the efficacy is doubtful. The lesions may be masked by use of cosmetic preparations. Vitiliginous areas should be protected from sunburn by applying a 5% aminobenzoic acid solution or gel to the affected areas. The use of 5% fluorouracil cream applied under an occlusive dressing to the depigmented areas may cause erosion of the dermis and, after re-epithelialization, pigment may reappear.

VITILIGO

vitiligo capitis

Vitiligo of the scalp with depigmentation of the hairs of the affected area.illustration

perinevic vitiligo

Vitiligo surrounding a nevus.

vitiligo

A skin disorder that features white patches, of variable size and shape, especially on the face, the backs of the hands, the armpits and around the anus. Vitiligo is inconspicuous in white people in winter but very obvious in black people or tanned whites. The affected areas of skin are deficient in pigment cells called melanocytes, but the cause of this is unclear. An immunological process is thought to be involved. Repigmentation can be achieved by taking a melanin precursor, L-phenylalanine, and then exposing the skin to ULTRAVIOLET LIGHT.

vitiligo 

A disease of the skin characterized by areas of depigmentation of various sizes and shapes. In the eye, it can be seen in the choroid or iris. It is often associated with syphilis or tuberculosis and forms part of the Vogt-Koyanagi-Harada syndrome. See poliosis.

vit·i·li·go

, pl. vitiligines (vit'i-lī'gō, -lij'nēz) [MIM*193200] The appearance on otherwise normal skin of nonpigmented white patches of varied sizes; hair in the affected areas is usually white. Epidermal melanocytes are completely lost in depigmented areas by an autoimmune process. [L. a skin eruption, fr. vitium, blemish, vice]

Patient discussion about vitiligo

Q. Is there any treatment for Vitiligo? Can anyone tell the how Vitiligo treated completelyA. Treatment of vitiligo is no doubt very tricky thing and may take too lang time and also cureless in some cases. But there are dozens of different treatment options are available for vitiligo.
The following are the possible treatment options for vitiligo skin disorder.
(1)Home Remedies
(2)Alternate treatments
(2.a)Oral therapies with natural Psoralen
(2.b)Topical therapies using natural Psoralen
(2.c)Homeopathic
(2.d)Ayer Vedic
(3)Prescription Medicine
(3.a)Topical steroid therapy
(3.b)Psoralen photochemotherapy
(4)Surgical Therapy
(4.a)Autologous skin grafts
(4.b)Skin grafts using blisters
(4.c)Autologous melanocyte transplants
(4.d)Totooing
Source: http://www.antivitiligo.com/vitiligo-treatment/

Q. Is Vitiligo Hereditary? A. Vitiligo may be hereditary in some cases. Children of vitiligo affected parents are more likely to develop vitiligo disorder. However, most children will not get vitiligo even if a parent has it. Also most people with vitiligo do not have a family history of the disorder.
Large number of inherited disorders are associated with vitiligo. They include: albinism of the ocular type, autoimmune polyendocrinopathy syndrome, congenital deafness with vitilego and achalasia, dyschromatosis symmetrica hereditaria, ermine phenotype, familial histiocyctic reticulosis, kabuki syndrome, and the syndrome of spastic paraparesis, vitiligo, premature graying and characteristic facies.
http://www.antivitiligo.com/

Q. How to Stop Vitiligo from spreading all over the body? Can any one please tell how to stop Vitiligo from spreading all over the bodyA. Normally treatment of vitiligo may take a long time. So patient should be relax and hopeful to treat this skin condition.
While start any treatment one thing is very important that not be depressed and anxious because this is the factor which can increase in vitiligo.
Take care when go out in afternoon.
Maintain a well balance diet plan which you can easily find by any dermatologist.
There are many treatment options are available for vitiligo as listed at http://www.antivitiligo.com/vitiligo-treatment/

More discussions about vitiligo
See VTLG
See VTLG

vitiligo

enUK
Related to vitiligo: Ceroid
  • noun

Words related to vitiligo

noun an acquired skin disease characterized by patches of unpigmented skin (often surrounded by a heavily pigmented border)

Related Words

  • disease of the skin
  • skin disease
  • skin disorder
  • hypopigmentation
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更新时间:2024/12/24 0:03:30