| 释义 |
prion protein disease prion protein disease One of a number of transmissible diseases, including CREUTZFELDT-JAKOB DISEASE, Gerstmann-Straussler syndrome and KURU, all of which feature a SPONGIFORM ENCEPHALOPATHY. They are all associated with an abnormal form of a normal cell protein called PRION PROTEIN. They feature plaques of AMYLOID in the brain tissue and the prion protein is the main constituent of these plaques. |