uremia

u·re·mi·a

also u·rae·mi·a U0141300 (yo͝o-rē′mē-ə)n. A toxic condition resulting from kidney disease in which there is retention in the bloodstream of waste products normally excreted in the urine. Also called azotemia.

u·re′mic adj.

uremia

(jʊˈriːmɪə) n (Pathology) the usual US spelling of uraemia uˈremic adj

u•re•mi•a

(yʊˈri mi ə)

n. the presence in the blood of excessive urea and other products normally excreted in the urine. [1855–60; ur-¹ + -emia] u•re′mic, adj.

uremia, uraemia

a toxic condition resulting from the presence of urinary constituents in the blood, caused by deficiencies in the secretion of urine. — uremic, uraemic, adj.See also: Blood and Blood Vessels

uremia

Poisoning by toxins accumulating in the body.

Thesaurus

Noun

uremia - accumulation in the blood of nitrogenous waste products (urea) that are usually excreted in the urineazotaemia, azotemia, uraemiapathology - any deviation from a healthy or normal condition

Translations

Urämie

uremia

(yo͝orē`mēə), condition resulting from advanced stages of kidney failure in which urea and other nitrogen-containing wastes are found in the blood. Uremia can be caused by NSAIDs (nonsteroid anti-inflammatory drugs), especially in older patients treated primarily with ibuprofenibuprofen
, nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxen and ketoprofen, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967.
..... Click the link for more information. for arthritis. Some of the early signs of uremia are lethargy, mental depression, loss of appetite, and edema; later symptoms include diarrhea, anemia, convulsions, coma, and a gray-brown coloration. Treatment of uremia, which is directed at the underlying kidney disease, is usually with dialysis and renal transplantation. Treatments with genetically engineered erythropoietin decrease the complication of anemia. See nephritisnephritis
, inflammation of the kidney. The earliest finding is within the renal capillaries (glomeruli); interstitial edema is typically followed by interstitial infiltration of lymphocytes, plasma cells, eosinophils, and a small number of polymorphonuclear leukocytes.
..... Click the link for more information. ; nephrosisnephrosis
, kidney disease characterized by lesions of the epithelial lining of the renal tubules, resulting in marked disturbance in the filtration function and the consequent appearance of large amounts of protein (albumin) in the urine (see urinary system).
..... Click the link for more information. .

Uremia

a toxic condition caused by severe impairment of renal function. It may be acute or chronic.

Acute uremia occurs in acute renal insufficiency during oliguria and is marked by severe impairment as well as by systemic disorders. The concentration of creatinine, urea, indican, ammonia, and other nitrogenous compounds increases markedly in the blood, resulting in azotemia. The content of such electrolytes as potassium, magnesium, calcium, and chlorine becomes altered, the acid-base balance is disturbed, resulting in acidosis, and water is retained in the body. Cardiovascular changes are manifested by tachycardia, arrhythmia, and hypertension. Other symtoms include anemia, digestive disorders, neurological disturbances, and often pulmonary edema. Acute uremia persists for five to ten days and sometimes up to 30 days or longer. The majority of persons affected with the disease return to work in three to 12 months.

Chronic uremia (terminal uremia, or terminal chronic renal insufficiency) is caused by many chronic kidney diseases. Affected persons experience lassitude, become emotionally unstable, and exhibit various types of neuromuscular phenomena. Hearing is impaired and the skin becomes pale yellow in color and is dry, flaccid, and painfully itchy. Other common symptoms are loss of appetite, nausea, vomiting, thirst, convulsions, polyneuritis, and nasal, cutaneous, or intestinal hemorrhages. The process of change in the electrolytes intensifies, and azotemia and acidosis become more marked. The bones decalcify and the joints are affected. Blood pressure rises sharply and pericarditis develops. The specific gravity of the urine remains low.

The treatment of uremia is conservative; methods used include cleansing of the blood by means of an artifical kidney or by peritoneal dialysis. A kidney transplant may be indicated.

REFERENCE

Osnovy nefrologii, vol. 1. Edited by E. M. Tareev. Moscow, 1972. Pages 164–234.

N. R. PALEEV

uremia

[yə′rē·mē·ə] (medicine) A condition resulting from kidney failure and characterized by azotemia, chronic acidosis, anemia, and a variety of systemic signs and symptoms.

uremia

[u-re´me-ah] 1. an excess in the blood of urea, creatinine, and other nitrogenous end products of protein and amino acid metabolism; more correctly referred to as azotemia.2. in current usage, the entire complex of signs and symptoms of chronic renal failure. As the rate" >glomerular filtration rate falls in either acute tubular necrosis or chronic renal failure, serum urea (usually expressed as blood urea nitrogen content or BUN) and creatinine rise to very high levels. However, BUN and creatinine measurements are only roughly correlated with uremic symptoms. Other nitrogenous compounds present in small amounts may produce most of the toxic effects. Some uremic symptoms are due to losses of kidney function that do not involve uremia (azotemia). adj., adj ure´mic.Patient Care. A major activity of care is assessment of health status and learning needs on an ongoing basis throughout the course of the illness. The systemic effects of uremia involve virtually every system of the body and present problems related to dysfunction of each system. Maintaining adequate nutrition is a very real challenge for the patient with this condition. The cooperative efforts of nutritionists and other health care professionals are needed to meet the goals of minimizing uremic toxicity, maintaining acceptable electrolyte levels, controlling hypertension, providing sufficient calories, and maintaining adequate nutritional status. Because of buildup of nitrogenous wastes from protein metabolism, dietary intake of protein may be severely limited. If any protein foods are allowed they should be of high quality; for example, eggs, milk, and cheese provide all of the essential amino acids in relatively small quantities.

Potassium restriction may also be indicated because of inability of the kidney to excrete it. This complicates the problem, however, because foods rich in potassium also are high-quality protein foods. These same foods also contain phosphorus, which may be restricted. A sodium-free diet usually is prescribed, but this can pose problems in regard to food selection and patient compliance.
Patients in the terminal stage of uremia will require special mouth care; measures to prevent pressure ulcers; protection from injury due to altered consciousness" >levels of consciousness; monitoring and protection from deleterious effects of excessive bleeding related to lack of renal hormone erythropoietin and bone marrow depression; and interventions appropriate to psychological and emotional support for the patient and family members during a terminal illness.

Systemic effects of uremia.

u·re·mi·a

(yū-rē'mē-ă), 1. An excess of urea and other nitrogenous waste in the blood. 2. The complex of symptoms due to severe persisting renal failure that can be relieved by dialysis. [G. ouron, urine, + haima, blood]

uremia

also

uraemia

(yo͝o-rē′mē-ə)n. A toxic condition resulting from kidney disease in which there is retention in the bloodstream of waste products normally excreted in the urine. Also called azotemia.

u·re′mic adj.

uremia

Prerenal azotemia, renal underperfusion Nephrology A constellation of Sx caused by the retention of urea and other products of protein catabolism due to inadequate kidney function in advanced renal failure Clinical N&V, pruritus, uremic frost, mental clouding, peripheral neuropathies, osteodystrophy, HTN, CHF, pericarditis, pulmonary edema Lab Acidosis, anemia, azotemia, ↓ Ca2+, ↑ PO₄, coagulopathy Pathogenesis 1º glomerular and/or tubular disease Management General support–restriction of protein, Na+, K+, and water; dialysis–hemodialysis, peritoneal dialysis; kidney transplant

Uremia

The presence of excessive amounts of urea and other waste products in the blood.Mentioned in: Alport Syndrome

u·re·mi·a

(yūr-ē'mē-ă) 1. Excess of urea and other nitrogenous waste in blood. 2. Complex of symptoms due to severe persisting renal failure that can be relieved by dialysis.
Synonym(s): uraemia. [G. ouron, urine, + haima, blood]

uremia

u·re·mi·a

uremia

u•re•mi•a

uremia, uraemia

uremia

uremia

uremia

Uremia

REFERENCE

uremia

uremia

uremia

u·re·mi·a

uremia

uraemia

uremia

Uremia

u·re·mi·a

uremia

Synonyms for uremia

noun accumulation in the blood of nitrogenous waste products (urea) that are usually excreted in the urine

Synonyms

Related Words