venous gangrene

stat·ic gan·grene

moist gangrene due to obstruction in the return circulation. Synonym(s): venous gangrene

venous gangrene

A rare condition defined as a clinical triad of skin necrosis and discolouration, documented evidence of venous thromboembolism (VTE) and presence of palpable or doppler-identifiable arterial pulsation, which in cancer patients is associated with poor prognosis. It is twice as common in patients with anticardiolipin antibodies.
Pathogenesis
Multifactorial; can paradoxically be due to warfarin treatment. Heparin Induced Thrombocytopenia (HIT)-associated VG develops when heparin therapy is discontinued and warfarin therapy initiated or continued.

单词	venous gangrene
释义	venous gangrene stat·ic gan·grene moist gangrene due to obstruction in the return circulation. Synonym(s): venous gangrene venous gangrene A rare condition defined as a clinical triad of skin necrosis and discolouration, documented evidence of venous thromboembolism (VTE) and presence of palpable or doppler-identifiable arterial pulsation, which in cancer patients is associated with poor prognosis. It is twice as common in patients with anticardiolipin antibodies. Pathogenesis Multifactorial; can paradoxically be due to warfarin treatment. Heparin Induced Thrombocytopenia (HIT)-associated VG develops when heparin therapy is discontinued and warfarin therapy initiated or continued.
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