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DictionarySeesclerosisprimary lateral sclerosis
primary lateral sclerosis[′prī‚mer·ē ′lad·ə·rəl sklə′rō·səs] (medicine) A sclerotic disease of the crossed pyramidal tracts of the spinal cord, characterized by paralysis of the limbs, with rigidity, increased tendon reflexes, and absence of sensory and nutritive disorders. Also known as lateral sclerosis. primary lateral sclerosis
pri·mar·y lat·er·al scle·ro·sisconsidered by many to be a subgroup of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski signs are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion. Synonym(s): lateral spinal sclerosispri·mar·y lat·er·al scle·ro·sis (prī'mar-ē lat'ĕr-ăl skler-ō'sis) Considered by many to be a subset of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski sign are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion. AcronymsSeePLS |