primary bile acid malabsorption

A primary congenital disorder (OMIM:613291) characterised by diarrhoea, steatorrhoea, interruption of the enterohepatic circulation of bile acids and reduced serum cholesterol.
Molecular pathology
Caused by defects of SLC10A2, which encodes an ileal-specific sodium/bile acid cotransporter that plays a key role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine, as well as in cholesterol metabolism.

单词	primary bile acid malabsorption
释义	primary bile acid malabsorption primary bile acid malabsorption A primary congenital disorder (OMIM:613291) characterised by diarrhoea, steatorrhoea, interruption of the enterohepatic circulation of bile acids and reduced serum cholesterol. Molecular pathology Caused by defects of SLC10A2, which encodes an ileal-specific sodium/bile acid cotransporter that plays a key role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine, as well as in cholesterol metabolism. AcronymsSeePBAM
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