TAL1


TAL1

A gene on chromosome 1p32 that encodes a protein which may play a key role in haematopoietic differentiation.
 
Molecular pathology
Defects in TAL1 may cause T-cell acute lymphoblastic leukaemia (T-ALL), in which there is a translocation t(1;14) (p32;q11) with T-cell receptor alpha chain (TCRA).