单词 | biofilm |
释义 | biofilmbi·o·filmB5265700 (bī′ō-fĭlm′)biofilm(ˈbaɪəʊˌfɪlm)biofilmBiofilmAn adhesive substance, the glycocalyx, and the bacterial community which it envelops at the interface of a liquid and a surface. When a liquid is in contact with an inert surface, any bacteria within the liquid are attracted to the surface and adhere to it. In this process the bacteria produce the glycocalyx. The bacterial inhabitants within this microenvironment benefit as the biofilm concentrates nutrients from the liquid phase. However, these activities may damage the surface, impair its efficiency, or develop within the biofilm a pathogenic community that may damage the associated environment. Microbial fouling or biofouling are the terms applied to these actual or potentially undesirable consequences. Microbial fouling affects a large variety of surfaces under various conditions. Microbial biofilms may form wherever bacteria can survive; familiar examples are dental plaque and tooth decay. Dental plaque is an accumulation of bacteria, mainly streptococci, from saliva. The process of tooth decay begins with the bacteria colonizing fissures in and contact points between the teeth. Dietary sucrose is utilized by the bacteria to form extracellular glucans that make up the glycocalyx and assist adhesion to the tooth. Within this microbial biofilm or plaque the metabolic by-products of the bacterial inhabitants are trapped; these include acids that destroy the tooth enamel, dentin, or cementum. biofilm[′bī·ō‚film]biofilmbiofilm[bi´o-film″]biofilm(bī'ō-film),biofilm(bī′ō-fĭlm′)biofilmMicrobiologyA slimy matrix of extracellular polymeric substances produced by bacteria which protects them when aggregated, as in dental plaque, the ear, intestine, skin, etc. Molecular biology A technique for immobilising cells by growing microorganisms on a thin layer of organic or inorganic materials including secreted polysaccharides and glycoproteins. bi·o·film(bī'ō-film)biofilmA slime-enclosed community of bacterial colonies that is very difficult to eradicate even with the most powerful antibiotics or sterilizing systems. Biofilms can occur on any body surface, on teeth (as dental plaque), medical equipment, medical tubing, contact lenses and elsewhere. They are held together by a matrix produced by the bacteria themselves and within this the bacteria communicate by chemical messengers, and generate proteins including enzymes that inactiovate some antibiotics. Biofilms also have major industrial and economic implications and are being intensively studied.biofilma collection of microbial CELLS covered by and embedded in a matrix of EXTRACELLULAR microbial POLYMERS, such as mucilage or slime, at an interface. Biofilms are found, for example, on the surface of stones in rivers and ponds, in water pipelines, as DENTAL PLAQUE on TEETH and on surgical implants. Microorganisms within biofilms appear to be less susceptible to BIOCIDES than their planktonic counterparts. The extracellular polymer and/or nutrient limitation associated with position of organisms in the film may alter sensitivity. Biofilms allow for the rapid spread of genetic material between the component microorganisms. Biofilm formation can have serious implications in industrial, environmental, medical and public health situations.bi·o·film(bī'ō-film) |
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