| 释义 |
PDE1A PDE1A A gene on chromosome 2q32.1 that encodes a cyclic nucleotide phosphodiesterase, which plays a critical role in signal transduction, regulating intracellular cyclic nucleotide concentrations by hydrolysing cAMP and/or cGMP to AMP and GMP. As with other PDE1s, PDE1A is activated by calmodulin in the presence of Ca2+. |