thymopoietin


thymopoietin

 [thi″mo-poi´ĕ-tin] a polypeptide hormone secreted by the thymus" >thymus; it induces the proliferation of lymphocyte precursors and their differentiation into lymphocytes" >T-lymphocytes.

thy·mo·poi·et·in

(thī'mō-poy-ē'tin), [MIM*188380] Formerly called thymin; a polypeptide hormone that induces differentiation of lymphocytes to thymocytes.
See also: thymic lymphopoietic factor.

TMPO

A gene on chromosome 12q22 that encodes thymopoietin, which may help direct nuclear lamina assembly and maintain the nuclear envelope’s structural organisation. Thymopoietin may act as a receptor for attachment of lamin filaments to the inner nuclear membrane.
Molecular pathology
Defects in TMPO cause cardiomyopathy dilated type 1.