vitamin B6 -dependency syndromes

vitamin B₆ -dependency syndromes

A group of functional or structural enzyme defects that respond to a megadoses–50-100-fold > minimum daily requirements of pyridoxine Examples Vitamin B₆-dependent convulsions, vitamin B₆-responsive anemia, xanthurenic aciduria, cystathioninuria, homocystinuria, possibly due to a defective structure of the apoenzyme, its coenzyme binding site or coenzyme synthesis Clinical Predominantly neurologic–eg, mental retardation, psychiatric Sx, seizures, convulsions, ataxia, spasticity, peripheral neuropathy

单词	vitamin b6 -dependency syndromes
释义	vitamin B6 -dependency syndromes vitamin B₆ -dependency syndromes A group of functional or structural enzyme defects that respond to a megadoses–50-100-fold > minimum daily requirements of pyridoxine Examples Vitamin B₆-dependent convulsions, vitamin B₆-responsive anemia, xanthurenic aciduria, cystathioninuria, homocystinuria, possibly due to a defective structure of the apoenzyme, its coenzyme binding site or coenzyme synthesis Clinical Predominantly neurologic–eg, mental retardation, psychiatric Sx, seizures, convulsions, ataxia, spasticity, peripheral neuropathy
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