单词 | srpk2 |
释义 | SRPK2SRPK2A gene on chromosome 7q22-q31.1 that encodes a serine/arginine-rich protein kinase which phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides (RS domains). SRPK2 plays a role in phosphorylating SR splicing factors and in regulating splicing. It promotes neuronal apoptosis by upregulating cyclin-D1 expression; it downregulates HBV replication by a non-phosphorylation mechanism, reducing the packaging efficiency of the pregenomic RNA without affecting the formation of the viral core particles. |
随便看 |
|
英语词典包含2567994条英英释义在线翻译词条,基本涵盖了全部常用单词的英英翻译及用法,是英语学习的有利工具。