| 释义 |
tricyclic antidepressant drug
Thesaurus| Noun | 1. | tricyclic antidepressant drug - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the braintricyclic, tricyclic antidepressantamitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medicationsantidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effectsclomipramine - a tricyclic antidepressant drugdesipramine - a tricyclic antidepressant drug that activates the psychomotor systemAdapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depressionnortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugsprotriptyline - tricyclic antidepressant used to treat clinical depressionSurmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia |
tricyclic antidepressant drug
tricyclic antidepressant drug One of a group of drugs whose structure is based on three six-carbon rings. The tricyclics produce an elevation of mood but this does not occur until the drugs have been taken for two to three weeks (an important point as depressed people may commit suicide during this period). These drugs have an anticholinergic effect and may cause dry mouth, constipation, urinary retention and blurred vision. The tricyclic antidepressants are the most widely used group for depression. They act by blocking the re-uptake of noradrenaline and serotonin at synapses thus allowing these stimulatory neurotransmitters to act for longer. With use, actual changes occur in the synapses that are of benefit. FLUOXETINE (Prozac) is not a tricyclic. It has only two rings and is a selective re-uptake inhibitor of serotonin only. Other tricyclic atidepressant drugs are AMITRIPTYLINE, DOXEPIN, IMIPRAMINE, NORTRIPTYLINE, and TRIMIPRAMINE. Up to 50 per cent of patients have genetic variations that prevent them from responding to these drugs.tricyclic antidepressant drug
Synonyms for tricyclic antidepressant drugnoun an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brainSynonyms- tricyclic
- tricyclic antidepressant
Related Words- amitriptyline
- amitriptyline hydrochloride
- Elavil
- antidepressant
- antidepressant drug
- clomipramine
- desipramine
- Adapin
- doxepin
- doxepin hydrochloride
- Sinequan
- Imavate
- imipramine
- impramine hydrochloride
- Tofranil
- nortriptyline
- Pamelor
- protriptyline
- Surmontil
- trimipramine
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