| 释义 |
self-tolerance
self-tol·er·ance (sĕlf′tŏl′ər-əns)n. Tolerance by the body's immune system to its own cells and tissues.EncyclopediaSeeToleranceself-tolerance
self-tolerance [self-tol´er-ans] immunological tolerance to self-antigens.hor·ror au·to·tox·'i·cusa term introduced by Ehrlich, meaning that immunity is directed against foreign materials but not against the constituents of one's own body; exceptions to this concept are the autoallergic reactions and diseases. Synonym(s): self-tolerance [L., dread of self-poisoning] self-tolerance (sĕlf′tŏl′ər-əns)n. Tolerance by the body's immune system to its own cells and tissues.self-tolerance immunological tolerance to the body's own ANTIGENS (self antigens), achieved by preventing the production of functional B-CELLS and T-CELLS reactive to such antigens. Thus the body is not able to direct an IMMUNE RESPONSE against self antigens. Breakdown of this mechanism leads to AUTOIMMUNITY and production of autoantibodies against self antigens.ThesaurusSeetolerance |