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squalene
squa·lene S0680000 (skwā′lēn′)n. An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as cholesterol. It is widely found in animals, plants, and fungi and is present in high concentrations in shark liver oil and human sebum.
[New Latin Squalus, shark genus (from its occurrence in the liver oil of sharks) (from Latin squalus, a sea fish) + -ene.]squalene (ˈskweɪˌliːn) n (Biochemistry) biochem a terpene first found in the liver of sharks but also present in the livers of most higher animals: an important precursor of cholesterol[C20: from New Latin squalus genus name of the shark]squa•lene (ˈskweɪ lin)
n. an oil, C30H50, intermediate in the synthesis of cholesterol, obtained for use in manufacturing pharmaceuticals. [1925–30; < New Latin Squal(us) a genus of sharks (the liver of which yields the oil), Latin: a kind of fish + -ene] Squalene
squalene[′skwā‚lēn] (biochemistry) C30H50 A liquid triterpene which is found in large quantities in shark liver oil, and which appears to play a role in the biosynthesis of sterols and polycyclic terpenes; used as a bactericide and as an intermediate in the synthesis of pharmaceuticals. Also known as spinacene. Squalene an aliphatic polyunsaturated liquid hydrocarbon with the formula C30H50. Squalene, which boils at 242°C and is soluble in many organic solvents, is an important intermediate in the metabolism of triterpenoids and steroids and is widely distributed in the tissues of animals and plants, as well as in microorganisms. It was first isolated from the liver of the shark. The biosynthesis of squalene is from mevalonic acid, which is converted to farnesyl pyrophosphate. The latter, under the action of squalenesynthetase (in the presence of thiamine), is di-merized to yield squalene. The enzymatic conversion of squalene to lanosterol and of lanosterol to cholesterol and other sterols commences with the aerobic oxidation of the terminal double bond of squalene. squalene
squalene [skwa´lēn] an unsaturated terpene that is an intermediate in cholesterol synthesis and occurs normally at low levels in blood plasma and at elevated levels in viral influenza; used as a vehicle for pharmaceuticals.squa·lene (skwā'lēn), A hexaisoprenoid (triterpenoid) hydrocarbon; intermediate in the biosynthesis of cholesterol and other sterols and triterpenes; found in shark oil and in some plants.squalene (skwā′lēn′)n. An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as cholesterol. It is widely found in animals, plants, and fungi and is present in high concentrations in shark liver oil and human sebum.squa·lene (skwā'lēn) A natural nonaromatic hydrocarbon found in plants and animals; a precursor of steroids including cholesterol. [L. squalus, shark] |