thrombomodulin


throm·bo·mod·u·lin

(throm'bō-mod'yū-lin), [MIM*188040] A glycoprotein present in the plasma membrane of endothelial cells that binds thrombin; participates in an additional regulatory mechanism in coagulation. [thrombo- + modulate + -in]

thrombomodulin

(thrŏm″bō-mō′dū-lĭn) A protein released by the vascular endothelium. Acting in concert with other factors, it helps to prevent formation of intravascular thrombi.

thrombomodulin

A receptor on ENDOTHELIUM that binds thrombin, inhibiting it clot-forming ability and causing it to activate protein C.