| Acronym | Definition |
|---|
| SPU➣Sripatum University (Thailand) |
| SPU➣Signal Processing Unit |
| SPU➣Split, Croatia (Airport Code) |
| SPU➣Seattle Pacific University |
| SPU➣Single Patient Use (medical products) |
| SPU➣Sardar Patel University (Vallabh Vidyanagar, Gujarat, India) |
| SPU➣Secretaría de Políticas Universitarias (Spanish: Secretariat of University Policies; Argentina) |
| SPU➣Seattle Public Utilities |
| SPU➣Special Protection Unit (various locations) |
| SPU➣Strategy and Policy Unit |
| SPU➣Socialist Party of Ukraine |
| SPU➣Southern Polytechnic University (Georgia) |
| SPU➣Southern Polytechnic University |
| SPU➣Segmented Polyurethane |
| SPU➣Service Pack Update |
| SPU➣Security Processing Unit |
| SPU➣Subpicture Decoding Unit |
| SPU➣Self Patch Utility |
| SPU➣Single Processor Unit |
| SPU➣Sound Processing Unit |
| SPU➣Synergistic Processor Unit |
| SPU➣Special Police Unit |
| SPU➣System Processing Unit |
| SPU➣Special Purpose Unit |
| SPU➣Single Package Unit |
| SPU➣Services Processing Unit (computing) |
| SPU➣Special Projects Unit (various organizations) |
| SPU➣Solar Panel Unit |
| SPU➣Somos un Pueblo Unido (Spanish: We Are a United Town; New Mexico) |
| SPU➣Short Procedure Unit (various hospitals) |
| SPU➣Solids Processing Unit |
| SPU➣State Power Utility (India) |
| SPU➣Safeguard Policy Update (Asian Development Bank) |
| SPU➣Society for Pediatric Urology |
| SPU➣Sheep Production Unit |
| SPU➣Sound Pick-Up |
| SPU➣Super Power Unit |
| SPU➣Sub-Picture Unit |
| SPU➣Service Production Unit |
| SPU➣Specialist, Utility (US Navy) |
| SPU➣Secure Processing Unit |
| SPU➣Strategic Procurement Unit |
| SPU➣Service de Pédagogie Universitaire (French: Department of University Education; University of Namur; Belgium) |
| SPU➣Subsystem Power Unit |
| SPU➣Socket Power Unit |
| SPU➣SAP Processing Unit |
| SPU➣Special Planning Unit |
| SPU➣S-Band Polar Ultra |
| SPU➣Sociedad Peruana de Urología |
| SPU➣Simulator Processor Unit |
| SPU➣Soybean Processing and Utilization Project (India) |
| SPU➣Service Publication Unit |
| SPU➣Stage Pré-Universitaire (French: Pre-University Course) |
| SPU➣Shard Productions Underground (online video group) |
| SPU➣Supra-Phrasal Unit (linguistics) |