| Acronym | Definition |
|---|
| SPSL➣South Puget Sound League (interscholastic sports league; Washington) |
| SPSL➣Security Policy Specification Language |
| SPSL➣Special-Purpose Simulation Language |
| SPSL➣Shree Precoated Steels Ltd. (India) |
| SPSL➣Short Period Superlattice |
| SPSL➣Steam Pressed Scrim Lumber |
| SPSL➣Slow Pitch Softball League (various locations) |