| Acronym | Definition |
|---|
| SPOF➣Single Point of Failure |
| SPOF➣Society for the Propagation of the Faith (Catholic Church) |
| SPOF➣Science Planning and Operations Facility (ISTP) |
| SPOF➣Strategic Plan for Ontario Fisheries (est. 1976; Ministry of Natural Resources; Canada) |
| SPOF➣Symmetric Phase Only Filtering |
| SPOF➣Screen Printers Open Forum |