| 单词 | rad1 |
| 释义 | RAD1RAD1A gene on chromosome 5p13.2 that encodes a protein of a heterotrimeric cell cycle checkpoint complex (9-1-1 complex), which is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites, where it attracts specialised DNA polymerases and other DNA repair effectors. |
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