adrenaline
a·dren·a·line
A0097600 (ə-drĕn′ə-lĭn)adrenaline
(əˈdrɛnəlɪn) oradrenalin
ep•i•neph•rine
or ep•i•neph•rin
(ˌɛp əˈnɛf rɪn)n.
a·dren·a·line
(ə-drĕn′ə-lĭn)Noun | 1. | ![]() |
单词 | adrenaline | |||
释义 | adrenalinea·dren·a·lineA0097600 (ə-drĕn′ə-lĭn)adrenaline(əˈdrɛnəlɪn) oradrenalinep•i•neph•rineor ep•i•neph•rin(ˌɛp əˈnɛf rɪn)n. a·dren·a·line(ə-drĕn′ə-lĭn)
adrenalineadrenaline rushadrenaline junkieadrenalineadrenaline(ədrĕn`əlĭn, –lēn): see epinephrineepinephrine, hormone important to the body's metabolism, also known as adrenaline. Epinephrine, a catecholamine, together with norepinephrine, is secreted principally by the medulla of the adrenal gland. ..... Click the link for more information. . Adrenaline(also epinephrine), a hormone of the medullary layer of the adrenal glands which plays an important part in the vital activity of animals and man. Adrenaline is a pyrocatechol derivative, l-methylaminoethanolpyro-catechol, with a molecular weight of 183.2. It is white, crystalline, and optically active. Soluble in hot water, acids, and bases, it is unstable and readily forms various transformation products. Adrenaline was isolated in 1901 and synthesized in 1905. It is formed from the amino acids phenylalanine and tyrosine in the chromaffinic (easily stained) granules of the adrenal glands, from where it is secreted into the bloodstream. The precursor of adrenaline in the organism is noradrenaline, a transmitter (mediator) of nerve impulses in the sympathetic nervous system. Upon entering the blood, the adrenaline raises the oxygen consumption of organs and tissues and participates in the mobilization of glycogen, the cleavage of which leads to an increase of the sugar level in the blood (hyperglycemia). Adrenaline stimulates protein, carbohydrate, fat, and mineral metabolism; raises arterial blood pressure (primarily by constricting the small peripheral blood vessels); increases heart and respiration rates and the force of cardiac contractions; slows intestinal peristalsis; and so forth. Adrenaline content of the blood rises during emotional stress, increased muscular work, choking, chilling, and lowering of the sugar level in the blood (hypoglycemia). A number of diseases of the internal organs, the nervous system, the endocrine glands, and of other parts of the body are accompanied by an increase or decrease of the adrenaline content in the organism, which can complicate the course of the disease. Adrenaline for therapeutic purposes is obtained from the adrenal glands of animals and also synthetically. An adrenaline hydrochloride solution is administered subcutaneously during drops in blood pressure and in cases of bronchial asthma and other allergic diseases, in local anesthesia, and for exsanguinating wounds during surgery. Sometimes it is used locally to stop bleeding. Adrenaline is contraindicated in cases of hypertension, atherosclerosis, and severe organic heart diseases. REFERENCESAdrenalin i noradrenalin. [Lectures of the conference held Dec. 1–3, 1962.] Moscow, 1964.Matlina, E. Sh., and V. V. Men’shikov. Klinicheskaia biokhimiia katekholaminov. Moscow, 1967. G. N. KASSIL’ adrenaline[ə′dren·əl·ən]adrenalineepinephrine[ep″ĭ-nef´rin]Some disorders of the adrenal glands, such as addison's disease, reduce the output of epinephrine below normal. By contrast, excessive activity of those glands, as sometimes seen in highly emotional persons, tends to produce tenseness, palpitation, high blood pressure, perhaps diarrhea, and overaggressiveness. Certain adrenal tumors also result in the production of too much epinephrine. Removal of the tumor relieves symptoms. Epinephrine is also produced synthetically and can be administered parenterally, topically, or by inhalation. It acts as a vasoconstrictor, antispasmodic, and sympathomimetic, and it is used as an emergency heart stimulant as well as to relieve symptoms in allergic conditions such as urticaria (hives), asthma, and other conditions requiring bronchodilation and as a adjunct to local and regional anesthesia. It is the most effective drug for counteracting the lethal effects of anaphylactic shock. It is also used topically in the eye in the treatment of glaucoma. ep·i·neph·rine(ep'i-nef'rin),See also: emergency theory, fight or flight response. adrenaline(ə-drĕn′ə-lĭn)adrenalineA sympathomimetic catecholamine hormone synthesised in the adrenal medulla and released into the circulation in response to hypoglycemia and sympathetic nervous system—i.e., splanchnic nerve stimulation due to exercise and stress; it acts on α- and β-receptors, resulting in vasoconstriction or vasodilation, decreased peripheral blood flow, increased heart rate, increased force of contractility, increased glycogenolysis and increased lipolysis. Pharmacologic doses of epinephrine are used as bronchodilator for acute asthma, to increase blood pressure and in acute myocardial infarctions, to improve myocardial and cerebral blood flow. Adrenaline is the official British pharmacopoeia name for epinephrine.adrenalineBritish for epinephrine, see there.ep·i·neph·rine(ep'i-nef'rin)Synonym(s): adrenaline. adrenalineEpinephrine, a HORMONE secreted by the inner part of the ADRENAL GLANDS. It is produced when unusual efforts are required. It speeds up the heart, increases the rate and ease of breathing, raises the blood pressure, deflects blood from the digestive system to the muscles, mobilizes the fuel glucose and causes a sense of alertness and excitement. It has been described as the hormone of ‘fright, fight and flight’. Adrenaline is available for use as a drug. Also known, especially in USA, as epinephrine.adrenalineorepinephrinea hormone secreted by the medulla (central part) of the ADRENAL GLAND. It prepares the body for emergency action (FIGHT-OR-FLIGHT REACTION); it increases the cardiac frequency, constricts the vessels supplying the skin and gut, increases the blood pressure, increases blood sugar, dilates the blood vessels of the muscles, heart and brain, widens the pupils, and causes hair erection. It is usually secreted with NORADRENALINE, whose effects are similar. Both hormones are also secreted by the ADRENERGIC nerve endings of the sympathetic nervous system.adrenaline (epinephrine)ep·i·neph·rine(ep'i-nef'rin)Synonym(s): adrenaline. adrenaline
Synonyms for adrenaline
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