oxalosuccinic carboxylase

i·so·cit·rate de·hy·dro·gen·ase

one of two enzymes that catalyze the conversion of threo-ds-isocitrate, the product of the action of both aconitase and isocitrate lyase, to α-ketoglutarate (2-oxoglutarate) and CO2; one of the isozymes uses NAD+ (participating in the tricarboxylic acid cycle), whereas the other uses NADP+. Synonym(s): isocitric acid dehydrogenase, oxalosuccinic carboxylase

oxalosuccinic carboxylase

An obsolete term for the isocitrate dehydrogenase enzymes (EC 1.1.1.41 and EC 1.1.1.42) that catalyse the two-step conversion of isocitrate lyase to alpha-ketoglutarate.