site-directed mutagenesis

site-·di·rec·ted mu·ta·gen·e·sis

the controlled alterations of selected regions of a DNA molecule.

site-directed mutagenesis

An experimental technique in which a mutation is inserted in DNA at a particular site to determine the site’s function, if any. In site-directed mutagenesis, nucleotides are altered, resulting in substitution of amino acids in a protein of known function, which serves to identify the DNA sequence’s role (e.g., as a receptor or ion channel).

单词	site-directed mutagenesis
释义	site-directed mutagenesis site-·di·rec·ted mu·ta·gen·e·sis the controlled alterations of selected regions of a DNA molecule. site-directed mutagenesis An experimental technique in which a mutation is inserted in DNA at a particular site to determine the site’s function, if any. In site-directed mutagenesis, nucleotides are altered, resulting in substitution of amino acids in a protein of known function, which serves to identify the DNA sequence’s role (e.g., as a receptor or ion channel).
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