Abeta


APP

A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.
Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).

Abeta

Amyloid beta peptide. It is the toxic peptide that causes damage to neurons in patients having Alzheimer disease.