单词 | usp47 |
释义 | USP47USP47A gene on chromosome 11p15.3 that encodes a deubiquitinase of the C19 peptidase family which acts on monoubiquitinated DNA polymerase beta (POLB), stabilising it and thereby playing a role in base-excision repair. USP47 regulates cell growth and genome integrity and may indirectly regulate CDC25A expression at a transcriptional level. |
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