单词 | usp11 |
释义 | USP11USP11A gene on chromosome Xp11.23 that encodes an enzyme which deubiquitinates target proteins, inhibiting their degradation by the proteasome. USP11 plays a role in regulating NF-kappaB activation pathways, as well as in regulating DNA repair after double-strand breaks. USP11 interacts with RANBP9/RANBPM, BRCA2, CHUK/IKKA, NFKBIA and HPV protein 16E7 |
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