ATP1B4

ATP1B4

A gene on chromosome Xq24 that encodes an enzyme belonging to the family of Na+/K+ and H+/K+ ATPases, which, while found in all vertebrates, has lost its ancestral function as a Na,K-ATPase beta-subunit in placental mammals (in which it interacts with the nuclear transcriptional coregulator SKIP); it may be involved in regulating TGF-beta signalling during muscle development through its interaction with SNW1.