microphthalmos


microphthalmos

 [mi″krof-thal´mus] a developmental defect causing moderate or severe reduction in size of the eye.

mi·croph·thal·mos

(mī'krof-thal'mos), Abnormal smallness of the eye. Synonym(s): microphthalmia, nanophthalmia, nanophthalmos [micro + G. ophthalmos, eye]

microphthalmia

A congenital reduction in eye size, with the ocular bulb measuring 1/2 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup.
Aetiology
• Congenital—e.g., encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15.
• Infectious—e.g., CMV, herpes, rubella, toxoplasmosis.
• Toxins—e.g., foetal alcohol syndrome.
Incidence
14/105; 3–11% of all cases of blindness.

mi·croph·thal·mos

(mī'krof-thal'mŏs) Abnormal smallness of the eye. [micro- + G. ophthalmos, eye]

microphthalmos

The state of having an abnormally small eyeball. In severe degrees there is usually a gross defect of vision.

mi·croph·thal·mos

, microphthalmia (mī'krof-thal'mŏs, -mē-ă) Abnormal smallness of the eye. [micro- + G. ophthalmos, eye]