单词	microphthalmia
释义	Microphthalmia Mi`croph`thal´mi`a n. 1. An unnatural smallness of the eyes, occurring as the result of disease or of imperfect development. microphthalmia microphthalmos  [mi″krof-thal´mus] a developmental defect causing moderate or severe reduction in size of the eye. mi·croph·thal·mos (mī'krof-thal'mos), Abnormal smallness of the eye. Synonym(s): microphthalmia, nanophthalmia, nanophthalmos [micro + G. ophthalmos, eye] microphthalmia A congenital reduction in eye size, with the ocular bulb measuring 1/2 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup. Aetiology • Congenital—e.g., encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15. • Infectious—e.g., CMV, herpes, rubella, toxoplasmosis. • Toxins—e.g., foetal alcohol syndrome. Incidence 14/105; 3–11% of all cases of blindness. microphthalmia A congenital ↓ in eye size, with the ocular bulb measuring1⁄2 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup, which may be 1. Congenital, as in encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz's microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15 or.2. Infectious–eg, CMV, rubella, toxoplasmosis. See TORCH. microphthalmia Congenital anomaly in which the eyeball is abnormally small and often deeply set in a small orbit. It is typically hyperopic. Syn. microphthalmos; microphthalmus. When there is no other abnormality (e.g. coloboma of the iris, microphthalmos with cyst), the condition is called nanophthalmos (Fig. M10). See anophthalmia; monophthalmia; pseudoptosis." >Fig. M10 Right eye microphthalmos (From Kanski 2007, with permission of Butterworth-Heinemann) mi·croph·thal·mos , microphthalmia (mī'krof-thal'mŏs, -mē-ă) Abnormal smallness of the eye. [micro- + G. ophthalmos, eye] ThesaurusSeenanophthalmos
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