MYO5B

A gene on chromosome 18q21 that belongs to the myosin gene superfamily, and is thought to be involved in plasma membrane recycling; vesicular trafficking in association with the CART complex; transport of NPC1L1 to the plasma membrane in a complex with RAB11A and RAB11FIP2; CFTR trafficking to the plasma membrane and TF (transferrin) recycling in non-polarised cells with RAB11A; epithelial cell polarisation with RAB11A and RAB8A; and trancytosis with RAB25.

Molecular pathology
MYO5B mutations are linked to microvillus inclusion disease.

单词	myo5b
释义	MYO5B MYO5B A gene on chromosome 18q21 that belongs to the myosin gene superfamily, and is thought to be involved in plasma membrane recycling; vesicular trafficking in association with the CART complex; transport of NPC1L1 to the plasma membrane in a complex with RAB11A and RAB11FIP2; CFTR trafficking to the plasma membrane and TF (transferrin) recycling in non-polarised cells with RAB11A; epithelial cell polarisation with RAB11A and RAB8A; and trancytosis with RAB25. Molecular pathology MYO5B mutations are linked to microvillus inclusion disease.
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