单词 | microcystin |
释义 | microcystinmicrocystin(mī-krō-sis'tin),microcystinAny toxic, cyclic, non-ribosomal peptide produced by cyanobacteria, which has anticholinesterase activity or causes severe liver injury through DNA damage by activating endonucleases and inhibiting inhibit protein phosphatases types 1 and 2A. Topical exposure to microcystins causes skin and eye irritation, rhinorrhoea, vertigo and fatigue; parenteral exposure may cause death after initial exposure, often due to intrahepatic haemorrhage and hypovolemic shock. An epidemic of microcystin-related death occurred at a haemodialysis centre in Brazil due to impure water. |
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