microcephaly
mi·cro·ceph·a·ly
M0271700 (mī′krō-sĕf′ə-lē)microcephaly
(ˌmaɪkrəʊˈsɛfəlɪ)mi•cro•ceph•a•ly
(ˌmaɪ kroʊˈsɛf ə li)n.
Noun | 1. | microcephaly - an abnormally small head and underdeveloped brain |
单词 | microcephaly | |||
释义 | microcephalymi·cro·ceph·a·lyM0271700 (mī′krō-sĕf′ə-lē)microcephaly(ˌmaɪkrəʊˈsɛfəlɪ)mi•cro•ceph•a•ly(ˌmaɪ kroʊˈsɛf ə li)n.
Microcephalymicrocephaly[‚mī·krō′sef·ə·lē]Microcephalysubstantial reduction in skull and brain size in the presence of normal dimensions of other parts of the body. Microcephaly is accompanied by mental deficiency, from mild imbecility to idiocy. The causes of microcephaly are viral diseases suffered by the mother during the first three months of pregnancy, toxoplasmosis, and, sometimes, intrauterine meningoencephalitis of the fetus. The prognosis is unfavorable. microcephalymicrocephaly[mi″kro-sef´ah-le]mi·cro·ceph·a·ly(mī'krō-sef'ă-lē),microcephaly(mī′krō-sĕf′ə-lē)microcephalyAn abnormally small head, which is usually associated with neurodevelopmental delay and mental retardation. A standard definition is any brain or head which is ≥ 3 standard deviations below the mean for a person’s age, sex, height, weight and race.Conditions associated with microcephaly Cockayne, Miller-Dieker, Smith-Lemli-Opitz, Rothmund-Thomson, and Wolf-Hirschhorn syndromes; chromosomal defects (cat-cry or 5p- and trisomy 13 syndromes), in utero infection (CMV), rubella, toxoplasmosis, toxic exposure (foetal alcohol and foetal hydantoin syndromes), radiation (the only confirmed congenital defect specifically linked to atomic bomb blasts (i.e., in Hiroshima and Nagasaki)), or trauma. Genes linked to microcephaly ASPM, CDK5RAP2, CENPJ, MCPH1, MCPH2, MCPH4. microcephalyNeonatology An abnormally small head, often associated with developmental delay and mental retardation; any brain or head that is ≥ 3 standard deviations below the mean for a person's age, sex, height, weight, race. Cf Macrocephaly.mi·cro·ceph·a·ly, microcephalia (mī'krō-sef'ă-lē, -sĕ-fālē-ă)Synonym(s): nanocephaly. microcephalyAbnormal smallness of the skull. Microcephaly often reflects poor brain development and is usually associated with MENTAL RETARDATION.MicrocephalyPaine,R.S.,mi·cro·ceph·a·ly, microcephalia (mī'krō-sef'ă-lē, -sĕ-fālē-ă)microcephaly
Synonyms for microcephaly
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