单词 | major breakpoint region |
释义 | major breakpoint regionmajor breakpoint regionA 150-bp region of DNA on chromosome 18q21, located in the 3’ untranslated region of bcl-2 exon III. 50–70% of t(14:18) translocations, which are seen in most follicular lymphomas, are linked to the major breakpoint region and are identified by PCR. |
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