释义 |
EncyclopediaSeeMichaelis ConstantMichaelis, Leonor
Michaelis, Leonor, German-U.S. chemist and physician, 1875-1949. Michaelis bufferMichaelis constant - the true dissociation constant for the enzyme-substrate binary complex in a single-substrate rapid equilibrium enzyme-catalyzed reaction. Synonym(s): Michaelis-Menten constantMichaelis-Gutmann body - a rounded homogenous body containing calcium and iron found within macrophages in the bladder wall in malacoplakia.Michaelis-Menten constant - Synonym(s): Michaelis constantMichaelis-Menten equation - an initial-rate equation for a single-substrate noncooperative enzyme-catalyzed reaction relating the initial velocity to the initial substrate concentration. Synonym(s): Victor-Michaelis-Menten equationMichaelis-Menten hypothesis - that a complex is formed between an enzyme and its substrate (the O'Sullivan-Tompson hypothesis), which complex then decomposes to yield free enzyme and the reaction products (Brown hypothesis), the latter rate determining the overall rate of substrate-product conversion.Victor-Michaelis-Menten equation - Synonym(s): Michaelis-Menten equation |