Michaelis-Gutmann body


Mi·chae·lis-Gut·mann bod·y

(mi-kā'lis gūt'mahn), a rounded homogeneous or concentrically laminated body, 1-10 mcm in diameter, containing calcium and iron; found within macrophages in malakoplakia.

Michaelis-Gutmann body

A lamellar, haematoxyphilic and refractile intracytoplasmic calcospherule seen by light microscopy, which is characteristic of malakoplakia.

Gutmann,

Carl, German physician, 1872–. Michaelis-Gutmann body - see under Michaelis

Michaelis,

Leonor, German-U.S. chemist and physician, 1875-1949. Michaelis bufferMichaelis constant - the true dissociation constant for the enzyme-substrate binary complex in a single-substrate rapid equilibrium enzyme-catalyzed reaction. Synonym(s): Michaelis-Menten constantMichaelis-Gutmann body - a rounded homogenous body containing calcium and iron found within macrophages in the bladder wall in malacoplakia.Michaelis-Menten constant - Synonym(s): Michaelis constantMichaelis-Menten equation - an initial-rate equation for a single-substrate noncooperative enzyme-catalyzed reaction relating the initial velocity to the initial substrate concentration. Synonym(s): Victor-Michaelis-Menten equationMichaelis-Menten hypothesis - that a complex is formed between an enzyme and its substrate (the O'Sullivan-Tompson hypothesis), which complex then decomposes to yield free enzyme and the reaction products (Brown hypothesis), the latter rate determining the overall rate of substrate-product conversion.Victor-Michaelis-Menten equation - Synonym(s): Michaelis-Menten equation