单词 |
mixed lymphocyte culture reaction |
释义 |
DictionarySeeMLCmixed lymphocyte culture reaction
mixed lym·pho·cyte cul·ture testa test for histocompatibility of HLA-D antigens in which donor and recipient lymphocytes are mixed in culture; the degree of incompatibility is indicated by the number of cells that have undergone transformation and mitosis, or by the uptake of radioactive isotope-labeled thymidine. Synonym(s): MLC testmixed lymphocyte culture reactionA laboratory test in which lymphocytes from different individuals are mixed to identify the presence of particular HLA class II antigens. The T cells from the “responder” will synthesize DNA and proliferate only if they do not have the same histocompatibility antigens as the “donor cells, ” homozygous cells with known HLA types. The donor cells are irradiated to prevent their proliferation during the test. AcronymsSeeMLCR |
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