Mixed lymphocyte culture


mixed lym·pho·cyte cul·ture test

a test for histocompatibility of HLA-D antigens in which donor and recipient lymphocytes are mixed in culture; the degree of incompatibility is indicated by the number of cells that have undergone transformation and mitosis, or by the uptake of radioactive isotope-labeled thymidine. Synonym(s): MLC test

mix·ed lym·pho·cyte cul·ture test

(mikst lim'fŏ-sīt kŭl'chŭr test) An assay for histocompatibility of human leukocyte antigens in which donor and recipient lymphocytes are mixed in culture; the degree of incompatibility is indicated by the number of cells that have undergone transformation and mitosis, or by the uptake of radioactive isotope-labeled thymidine.

Mixed lymphocyte culture (MLC)

Test that measures level of reactivity between donor and recipient lymphocytes.Mentioned in: Bone Marrow Transplantation