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单词 lassa fever
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Lassa fever


Las·sa fever

L0145400 (lä′sə, lăs′ə)n. An acute form of hemorrhagic fever endemic to West Africa that is caused by an arenavirus transmitted by a species of rat and is characterized by fever, headache, gastrointestinal symptoms, and bleeding from the gums, and can result in deafness.
[After Lassa, a village of northeast Nigeria.]

Lassa fever

n (Pathology) a serious viral disease of Central West Africa, characterized by high fever and muscular pains [named after Lassa, the village in Nigeria where it was first identified]

Las′sa fe′ver

(ˈlɑ sə)
n. an infectious, often fatal disease characterized by fever and pharyngitis, caused by an arenavirus. [1965–70; after Lassa, Nigeria, village where it was first identified]
Thesaurus
Noun1.Lassa fever - an acute contagious viral disease of central western Africa; characterized by fever and inflammation and muscular pains and difficulty swallowing; can be used as a bioweaponhaemorrhagic fever, hemorrhagic fever, VHF, viral haemorrhagic fever, viral hemorrhagic fever - a group of illnesses caused by a viral infection (usually restricted to a specific geographic area); fever and gastrointestinal symptoms are followed by capillary hemorrhage

Lassa fever


Lassa fever

(lăs`ə), an acute viral disease occurring mostly in W Africa, characterized by high fever, muscle aches, mouth ulcers, and bleeding in the skin in more severe cases. The disease was first recognized in Lassa, Nigeria, in 1969. The causative virus is an arenavirus and is harbored by a rat, Mastomys natalensis. The virus is spread to humans via the rat's urine in airborne droplets or contaminated food. The disease can also be caught by medical personnel treating patients in hospitals.

The incubation period of Lassa fever is 3 to 17 days. In some 80% of the cases the symptoms are mild and typically undiagnosed. In more serious cases, following fever and general malaise, later stages of the disease may include abdominal pain, diarrhea, vomiting, and petechiae, tiny purplish spots in the skin caused by leakage of blood from the capillaries. Heart and kidney failure may also occur in severe cases. Although only an estimated 1% die from the disease, mortality is high among those hospitalized with Lassa fever, ranging from about 15% to, among pregnant women, as much as 60%. In epidemics, however, about half of all hospitalized patients may die, and spontaneous abortion occurs in 95% of infected pregnant women. Treatment by injection of the antiviral drug ribavirin is often successful if begun early.

See also hemorrhagic feverhemorrhagic fever
, any of a group of viral diseases characterized by sudden onset, muscle and joint pain, fever, bleeding, and shock from loss of blood. Bleeding occurs in the form of leakage from capillaries in the internal organs and the skin and mucous membranes.
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Lassa fever

[′läs·ə ‚fē·vər] (medicine) An acute, highly communicable exotic infection that is endemic in western Africa. Caused by an arenavirus (the Lassa virus), it is characterized by high fever, weakness, headaches, mouth ulcers, hemorrhages under the skin, heart and kidney failure, and a high mortality rate.

Lassa fever

a serious viral disease of Central West Africa, characterized by high fever and muscular pains

Lassa fever


Lassa fever

 [las´ah] a highly fatal acute type of hemorrhagic fever caused by a virulent arenavirus, occurring in West Africa, and characterized by progressive prostration, sore throat, ulcerations of the mouth or throat, rash, and general aches and pains, which may be followed by serous effusions, generalized hemorrhages, and fatal shock.

Las·sa fe·ver

a severe form of epidemic hemorrhagic fever, which is usually fatal. It was first recognized in Lassa (Nigeria); caused by the Lassa virus, a member of the Arenaviridae family; is characterized by high fever, sore throat, severe muscle aches, skin rash with hemorrhages, headache, abdominal pain, vomiting, and diarrhea. The multimammate rat Mastomys natalensis serves as reservoir, but person-to-person transmission is also common. Synonym(s): Lassa hemorrhagic fever

Lassa fever

(lä′sə, lăs′ə)n. An acute form of hemorrhagic fever endemic to West Africa that is caused by an arenavirus transmitted by a species of rat and is characterized by fever, headache, gastrointestinal symptoms, and bleeding from the gums, and can result in deafness.

Las·sa fe·ver

(lah'să fē'vĕr) A severe form of epidemic hemorrhagic fever that is highly fatal. It was first recognized in Lassa, Nigeria; is caused by the Lassa virus, a member of the Arenaviridae family, and characterized by high fever, sore throat, severe muscle aches, rash with hemorrhages, headache, abdominal pain, vomiting, and diarrhea. The multimammate rat Mastomys natalensis serves as a reservoir, but person-to-person transmission is also common.

Lassa fever

An infectious disease caused by an arenavirus and first noted in 1969 in West Africa. The disease is maintained in the rat population and spread by rat urine. Lassa fever features a high temperature for 7 to 17 days, slow pulse, sore throat, red eyes, prostration, vomiting and pain in the chest wall and abdomen. Yellow spots and ulcers appear on the tonsils. There is a drop in the white cell count in the blood (leukopenia), internal bleeding and often liver and kidney failure. The most severely affected pass into coma and die of inadequate circulation (shock), respiratory insufficiency, or cardiac arrest. The mortality rate may be as high as 50% but many mild cases occur. Strict isolation is necessary. Treatment is with the antiviral drug RIBAVIRIN and with plasma from convalescent patients.

Lassa fever


  • noun

Words related to Lassa fever

noun an acute contagious viral disease of central western Africa

Related Words

  • haemorrhagic fever
  • hemorrhagic fever
  • VHF
  • viral haemorrhagic fever
  • viral hemorrhagic fever
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