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osteoprotegerin
osteoprotegerin[¦äs·tē·prō′teg·ərin] (biochemistry) A protein that plays a central role in regulating bone mass. osteoprotegerin
os·te·o·pro·teg·er·in (OPG), (os'tē-ō-prō-tej'ĕr-in), Polypeptide suppressing osseous mineral turnover deficient in juvenile onset Paget disease. [osteo- + L. protego, protegere, to protect, + -in] os·te·o·pro·teg·er·in (os'tē-ō-prō-tej'ĕr-in) A secreted protein that inhibits osteoclast differentiation. [osteo- + L. protego, protegere, to protect, + -in]osteoprotegerin (OPG) A secreted protein which inhibits osteoclast differentiation. The cytokine TRANCE binds to osteoprotegerin. Recombinant osteoprotegerin has been used successfully to treat juvenile PAGET'S DISEASE.AcronymsSeeÖPG |