| 单词 | admixture mapping |
| 释义 | admixture mappingadmixture mappingGene mapping of populations of mixed ancestry—e.g., African Americans, Latino/Hispanics—to identify gene loci responsible for differences in disease frequencies. Admixture mapping attempts to correlate the degree of ancestry near a gene locus to a disease or trait of interest, and assumes that differences in disease rates are linked to differences in the frequencies of disease-causing genetic variants between populations. In an admixed population, these causal variants occur more frequently on chromosomal segments inherited from one or the other ancestral population. |
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