mustine

mechlorethamine

A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.
Global village
Mechlorethamine was first developed as a chemical weapon.
Oncology
A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
 
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.

mustine

Chlormethine, a drug used to treat some cases of HODGKIN'S DISEASE. It is very toxic and is liable to cause severe vomiting.