maturity onset diabetes of the young type 7

An autosomal dominant (OMIM:610508) condition characterised by diabetes of childhood or early-adulthood onset (usually before 25 years of age), a primary defect in insulin secretion and insulin-independence at the beginning of the disease.
Molecular pathology
Caused by defects in KLF11, which encodes a zinc finger transcription factor that binds SP1-like sequences in epsilon- and gamma-globin gene promoters, inhibiting cell growth and causing apoptosis.

单词	maturity onset diabetes of the young type 7
释义	maturity onset diabetes of the young type 7 maturity onset diabetes of the young type 7 An autosomal dominant (OMIM:610508) condition characterised by diabetes of childhood or early-adulthood onset (usually before 25 years of age), a primary defect in insulin secretion and insulin-independence at the beginning of the disease. Molecular pathology Caused by defects in KLF11, which encodes a zinc finger transcription factor that binds SP1-like sequences in epsilon- and gamma-globin gene promoters, inhibiting cell growth and causing apoptosis.
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