单词 | maturation inhibitors |
释义 | maturation inhibitorsmaturation inhibitorsAn experimental class of anti-HIV drugs that block protease action in a manner different from that of PROTEASE INHIBITORS. Maturaltion inhibitors act by blocking a site on the GAG protein where protease normally binds, that preventing the enzyme from clipping GAG correctly. In this way the capsid does not form and the virus is unable to infect other cells. A member of the class is a betulinic acid derivative called PA-457. |
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