释义 |
DictionarySeesequestrantbile acid sequestrant
bile acid sequestrant Any of a family of cholesterol-lowering agents—e.g., cholestipol, cholestyramine—that bind with cholesterol-containing bile acids in the intestine and remove them in stool. Adverse effects Constipation, diarrhoea, flatulence.bile acid sequestrant Any of a class of polymeric resins that binds bile acids and prevents these cholesterol-containing compounds from recirculating into the blood from the gastrointestinal tract. Medications from this class are used to treat those with high serum cholesterol levels and to reduce itching in patients with chronic liver diseases. See also: sequestrantbile acid sequestrant A drug that binds to bile acids that have entered the intestine via the bile duct, so altering them that they cannot be absorbed back into the bloodstream in the usual way and are excreted in the faeces. Cholesterol is converted to bile acids by the liver. Loss of bile acids means more conversion of cholesterol and a lowering in total body cholesterol.AcronymsSeeBAS |