antipsychotic

an·ti·psy·chot·ic

A0347200 (ăn′tē-sī-kŏt′ĭk, ăn′tī-)adj. Counteracting or diminishing the symptoms of psychotic disorders, such as schizophrenia.n. An antipsychotic drug.

antipsychotic

(ˌæntɪsaɪˈkɒtɪk) adj (Psychiatry) preventing or treating psychosisn (Pharmacology) any antipsychotic drug, such as chlorpromazine: used to treat such conditions as schizophrenia

an•ti•psy•chot•ic

(ˌæn ti saɪˈkɒt ɪk, ˌæn taɪ-)

adj. 1. of or pertaining to any of various drugs used in the treatment of psychosis, esp. schizophrenia, and severe states of mania, depression, or paranoia. n. 2. Also called neuroleptic. an antipsychotic drug. [1950–55]

Thesaurus

Noun

antipsychotic - tranquilizer used to treat psychotic conditions when a calming effect is desiredantipsychotic agent, antipsychotic drug, major tranquilizer, major tranquilliser, major tranquillizer, neuroleptic, neuroleptic agent, neuroleptic drugchlorpromazine, Thorazine - a drug (trade name Thorazine) derived from phenothiazine that has antipsychotic effects and is used as a sedative and tranquilizerclozapine, Clozaril - an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effectsdiphenylbutyl piperidine - a group of antipsychotic drugs used mainly in the treatment of schizophreniafluphenazine - tranquilizer used to treat psychotic disordersHaldol, haloperidol - tranquilizer (trade name Haldol) used to treat some psychotic disorders and Tourette's syndromeloxapine, Loxitane - a tranquilizer (trade name Loxitane) used to treat schizophreniaMoban, molindone - antipsychotic drug (trade name Moban) used in the treatment of schizophreniaprochlorperazine - antipsychotic and antiemetic drug used to treat schizophrenia and to combat nausea and vomitingMellaril, thioridazine - a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disordersNavane, thiothixene - a tranquilizer (trade name Navane) used to treat schizophreniaantianxiety agent, ataractic, ataractic agent, ataractic drug, tranquilizer, tranquilliser, tranquillizer - a drug used to reduce stress or tension without reducing mental clarityEskalith, Lithane, lithium carbonate, Lithonate - a white powder (LiCO3) used in manufacturing glass and ceramics and as a drug; the drug (trade names Lithane or Lithonate or Eskalith) is used to treat some forms of depression and manic episodes of manic-depressive disorder

Translations

antipsychotic

[an″te-, an″ti-si-kot´ik] modifying psychotic behavior.antipsychotic agent.antipsychotic agent any drug that favorably modifies psychotic" >psychotic symptoms; categories include the phenothiazines, butyrophenones, thioxanthenes, dibenzodiazepines, diphenylbutylpiperidines, dihydroindolones, and dibenzoxazepines. They are chemically diverse but pharmacologically similar. Formerly called major tranquilizer.
Antipsychotics stabilize mood and reduce anxiety, tension, and hyperactivity. They are also effective in helping to control agitation and aggressiveness. Delusions and hallucinations are often modified and may be eliminated by such an agent, but once the drug is discontinued, the delusions and hallucinations often return within a short while. Different antipsychotic agents bind to dopamine, histamine, muscarinic, cholinergic, α-adrenergic, and serotonin receptors. Blockade of dopaminergic transmission in various areas is thought to be responsible for the major antipsychotic, antiemetic effects of these agents as well as neurologic side effects. The drugs are contraindicated in patients suffering from central nervous system depression, severe allergy, Parkinson's disease, or a blood dyscrasia. There also is the possibility of drug-drug interaction when neuroleptic drugs are given concurrently with barbiturates, alcohol, tricyclic antidepressants, antihypertensives, meperidine, anticonvulsants, or levodopa.
Many antipsychotics have alarming side effects (see extrapyramidal effects); thus there must be thorough patient education and individualized adjustments in dosage. The side effects can usually be minimized by gradually increasing the dosage until the optimum for the individual is reached. Side effects such as a discomforting restlessness and agitation (akathisia), involuntary rhythmic movements of the trunk and limbs, parkinsonism, and dyskinesia" >tardive dyskinesia are often misinterpreted as symptoms of some unrelated disorder; these are often the reason for noncompliance or stopping of medication by patients. Approximately 20 per cent of the patients treated with neuroleptics for long periods develop tardive dyskinesia, a syndrome of choreoathetoid movements of the tongue, mouth, face, neck, limbs, and trunk, which may continue after the drug is stopped.
Antipsychotic agents are sometimes prescribed for conditions other than mental disorders. They can be beneficial in the control of nausea, in the treatment of intractable hiccups, in controlling the movement disorders associated with Huntington's chorea and Gilles de la Tourette's syndrome, and, in combination with other drugs, for the control of pain.

an·ti·psy·chot·ic

(an'tē-sī-kot'ik), 1. Synonym(s): antipsychotic agent2. Denoting the actions of such an agent (for example, chlorpromazine).

antipsychotic

(ăn′tē-sī-kŏt′ĭk, ăn′tī-)adj. Counteracting or diminishing the symptoms of psychotic disorders, such as schizophrenia.n. An antipsychotic drug.

antipsychotic

adjective Referring to an antipsychotic drug.
noun Any drug that attenuates psychotic episodes.

Agents
Phenothiazines, thioxanthenes, butyrophenones, dibenzoxazepines, dibenzodiazepines, diphenylbutylpiperidines.

Main types of antipsychotics
Typical and atypical, which differ in their side/adverse effects.

Indications
Management of schizophrenic, paranoid, schizo-affective and other psychotic disorders; acute delirium, dementia, manic episodes (during induction of lithium therapy), control of movement disorders (in Huntington’s disease), Tourette syndrome, ballismus, intractable hiccups, severe nausea and vomiting (by blocking the medulla’s chemoreceptor trigger zone).

Adverse effects
Extrapyramidal effects (dystonia, akathisia, parkinsonism), tardive dyskinesia due to blocking of basal ganglia; sedation and autonomic side effects (orthostatic hypotension, blurred vision, dry mouth, nasal congestion and constipation) are due to blocking of histaminic, cholinergic and adrenergic receptors.

an·ti·psy·chot·ic

(an'tē-sī-kot'ik) 1. Synonym(s): antipsychotic agent. 2. Denoting the actions of such an agent.

antipsychotic

A drug used in the treatment or control of severe mental illness such as SCHIZOPHRENIA. The antipsychotic drugs include such groups as the benzamides (Amisulpride, Dolmatil, Solian); benzisoxzoles (Risperidal); butyrophenones (Anquil, Dozic, Droleptan, Haldol, Serenace); phenothiazines (Fentazin, Largactil, Melleril, Modecate, Moditen, Neulactil, Nozinan, Stelazine); and thioxanthines (Clopixol, Depixol).

an·ti·psy·chot·ic

(an'tē-sī-kot'ik) 1. Synonym(s): antipsychotic agent. 2. Denoting the actions of such an agent (e.g., chlorpromazine).

antipsychotic

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antipsychotic

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Synonyms for antipsychotic

noun tranquilizer used to treat psychotic conditions when a calming effect is desired

Synonyms

Related Words