单词 | methionine aminopeptidase-2 |
释义 | methionine aminopeptidase-2methionine aminopeptidase-2A cobalt- and magnesium-binding cytoplasmic methionyl aminopeptidase encoded by METAP2 on chromosome 12q22, which plays a key role in regulating post-translational processing and protein synthesis, by hydrolysing N-terminal methionine from newly synthesized proteins. It is a molecular target for angiogenesis inhibitors and thus has therapeutic potential in tumour progression, diabetic retinopathy, rheumatoid arthritis, and other conditions characterised by angiogenesis. |
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