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单词 macroglobulin
释义

macroglobulin

enUK

mac·ro·glob·u·lin

M0015000 (măk′rō-glŏb′yə-lĭn)n. A plasma globulin of high molecular weight.

macroglobulin

(ˌmækrəʊˈɡlɒbjʊlɪn) n1. (Biochemistry) an immunoglobulin of unusually high relative molecular mass, observed in the blood in some diseases2. (Biochemistry) Also called: immunoglobulin M the normal form of this immunoglobulin

macroglobulin

enUK

macroglobulin

[¦mak·rə′gläb·yə·lən] (biochemistry) Any gamma globulin with a sedimentation constant of 195.

macroglobulin

enUK

macroglobulin

 [mak″ro-glob´u-lin] a protein (globulin) of high molecular weight, in the range of 1,000,000; observed in the blood in a number of diseases.α2-macroglobulin a plasma protein that inhibits a wide variety of proteolytic enzymes, including trypsin, plasmin, thrombin, kallikrein, and chymotrypsin, by entrapping and reducing the accessibility of their functional sites to large molecules. Written also alpha2-macroglobulin.

macroglobulin

(măk′rō-glŏb′yə-lĭn)n. A plasma globulin of high molecular weight.

macroglobulin

Any large serum protein, usually ≥ 400 kD—e.g., IgM (900 kD), α2-macroglobulin (820 kD). Macroglobulins are detected by sharp peaks on a simple zone electrophoresis, usually in the gamma region; because of the differing charges on the radicals, the electrophoretic mobility (pI) on the agar may shift and monoclonal spikes may occur in the beta or, less commonly, in the alpha region.

macroglobulin

Any large serum protein, usually ≥ 400 kD–eg, IgM–900 kD, α2-macroglobulin–820 kD; macroglobulins are detected by sharp peaks on a simple zone electrophoresis, usually in the γ-region

macroglobulin

See IgM.
ThesaurusSeeimmunoglobulin M
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