释义 |
base substitution base substitution The replacement of a single nucleotide in a nucleic acid (e.g., in DNA or RNA) which can be silent—due to “degeneracy” of DNA, in which multiple codons encode the same amino acid—or result in a point mutation with a substituted amino acid or premature termination of transcription or translation.base substitution replacement of a NUCLEOTIDE base in a DNA molecule with another base, possibly producing a SUBSTITUTION MUTATION. |