metanephrine

[met″ah-nef´rin] a urinary metabolite of epinephrine.

met·a·neph·rine

(met-ă-nef'rin), A catabolite of epinephrine found in the serum, urine and in some tissues, resulting from the action of catechol-O-methyltransferase on epinephrine; has no sympathomimetic actions; 3-O-methylepinephrine.

metanephrine

Any exogenous or endogenous catecholamine metabolite excreted in the urine (normal adults, 0.03–0.69 mmol/mol creatinine). Metanephrines are elevated in neuroblastoma, pheochomocytoma, metastases, stress and sepsis.

False positive elevation
High dietary intake of bananas, or therapy with chlopromazine, corticosteroids, l-dopa, dopamine, guanethidine, hydralazine, imipramine, nalidixic acids, phenobarbital, phenylephrine, or tetracycline.

False negative reduction
Clonidine, guanethidine, propranolol, reserpine.

Ref range
24–288 µg/24 hours; US, 0.05–1.2 mg/24 hours.

Specimen
24-hour urine.

Method
HPLC.

metanephrine

Methoxyepinephrine Lab medicine Any exogenous or endogenous catecholamine metabolite excreted in the urine; metnephrines ↑ in neuroblastoma, pheochomocytoma, metastases, stress, sepsis

met·a·neph·rine

(met'ă-nef'rin) A metabolite of epinephrine, excreted in the urine and found in some tissues.

met·a·neph·rine

(met'ă-nef'rin) A catabolite of epinephrine found in the serum, urine, and some tissue types, due to action of catechol-O-methyltransferase on epinephrine.

单词	metanephrine
释义	metanephrine Translations metanephrine metanephrine [‚med·ə′ne‚frən] (biochemistry) An inactive metabolite of epinephrine (3-O-methylepinephrine) that is excreted in the urine; it is recovered and measured as a test for pheochromocytoma. metanephrine metanephrine [met″ah-nef´rin] a urinary metabolite of epinephrine. met·a·neph·rine (met-ă-nef'rin), A catabolite of epinephrine found in the serum, urine and in some tissues, resulting from the action of catechol-O-methyltransferase on epinephrine; has no sympathomimetic actions; 3-O-methylepinephrine. metanephrine Any exogenous or endogenous catecholamine metabolite excreted in the urine (normal adults, 0.03–0.69 mmol/mol creatinine). Metanephrines are elevated in neuroblastoma, pheochomocytoma, metastases, stress and sepsis. False positive elevation High dietary intake of bananas, or therapy with chlopromazine, corticosteroids, l-dopa, dopamine, guanethidine, hydralazine, imipramine, nalidixic acids, phenobarbital, phenylephrine, or tetracycline. False negative reduction Clonidine, guanethidine, propranolol, reserpine. Ref range 24–288 µg/24 hours; US, 0.05–1.2 mg/24 hours. Specimen 24-hour urine. Method HPLC. metanephrine Methoxyepinephrine Lab medicine Any exogenous or endogenous catecholamine metabolite excreted in the urine; metnephrines ↑ in neuroblastoma, pheochomocytoma, metastases, stress, sepsis met·a·neph·rine (met'ă-nef'rin) A metabolite of epinephrine, excreted in the urine and found in some tissues. met·a·neph·rine (met'ă-nef'rin) A catabolite of epinephrine found in the serum, urine, and some tissue types, due to action of catechol-O-methyltransferase on epinephrine.
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