| 单词 |
neuroserpin |
| 释义 |
neuroserpin neu·ro·ser·pin (nūr-ō-sĕr-pin), Axonally released neuronal serine protease inhibitor found in cortical and hippocampal neurons; a familial form of presenile dementia has been linked to mutations of neuroserpins; mutant neuroserpins form polymers or inclusion bodies result in neuronal degenerationSERPINI1 A gene on chromosome 3q26.1 that encodes a member of the serpin superfamily of serine proteinase inhibitors that inhibits tissue-type plasminogen activator. It is secreted by axons in the brain and thought to play a role in regulating axonal growth and the development of synaptic plasticity or the reorganisation of synaptic connections. SERPINI1 may protect neurons from cell damage by tissue-type plasminogen activator.
Molecular pathology
SERPINI1 mutations cause familial encephalopathy with neuroserpin inclusion bodies (FENIB), an autosomal dominant form of familial encephalopathy and epilepsy. |
| 随便看 |
- potassium tartrate
- potassium t-butoxide
- potassium tert-butoxide
- potassium tetraiodocadmate
- potassium thiocyanate
- potassium thiocyanide
- potassium titanate whisker
- potassium titanyl phosphate
- potassium titanyl phosphate laser
- potassium-transporting atpase alpha chain 1
- potassium-transporting atpase beta chain
- potassium-transporting atpase subunit beta
- potassium tri-polyphosphate
- potassium undecylenate
- potassium, urine
- potassium valerate
- potassium voltage-gated channel, isk-related family, member 1
- potassium voltage-gated channel, isk-related family, member 2
- potassium voltage-gated channel, isk-related family, member 3
- potassium voltage-gated channel, isk-related family, member 4
- potassium voltage-gated channel, isk-related subfamily, member 1
- potassium voltage-gated channel, kqt-like subfamily, member 1
- potassium voltage-gated channel, kqt-like subfamily, member 2
- potassium voltage-gated channel, kqt-like subfamily, member 3
- potassium voltage-gated channel, kqt-like subfamily, member 4
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